Publications

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Most Recent 

  •  Zhang L, Silva TC, Young JI, Gomez L, Schmidt MA, Hamilton-Nelson KL, Kunkle BW, Chen X, Martin ER, Wang L* (2020). Epigenome-wide meta-analysis of DNA methylation differences in prefrontal cortex implicates the immune processes in Alzheimer’s disease. Nature Communications. In Press. 
  • Y Zhang, P Wang, X Li, S Ning, X Li, Y Cao,  SX Chen* (2020) GABC: A Comprehensive Resource and Genome Atlas for Breast Cancer. International Journal of Cancer. In Press. 
  • Colaprico A, Olsen C, Bailey MH, Odom GJ, Terkelsen T, Silva TC, Olsen AV, Cantini L, Zinovyev A, Barillot E, Noushmehr H, Bertoli G, Castiglioni I, Cava C, Bontempi G, Chen XS*, Papaleo E* (2020). Interpreting pathways to discover cancer driver genes with Moonlight. Nature Communications. 11(1):69. 
  • Odom GJ, Ban Y, Colaprico A, Liu L, Silva TC, Sun X, Pico AR, Zhang B, Wang L*, Chen X* (2020) pathwayPCA: an R package for integrative pathway analysis with modern PCA methodology and gene selection. Proteomics. In Press. 
  • Gomez L, Odom GJ, Young JI, Martin ER, Liu L, Chen X, Griswold AJ, Gao Z, Zhang L, Wang L* (2019). coMethDMR: accurate identification of co-methylated and differentially methylated regions in epigenome-wide association studies with continuous phenotypes. Nucleic Acids Research. 47(17):e9 
  • Mallik S, Odom GJ, Gao Z, Gomez L, Chen X*, Wang L* (2019). An evaluation of supervised methods for identifying differentially methylated regions in Illumina methylation arrays. Brief Bioinform. 20(6):2224-35

 Prediction models for personalized disease risk assessment using genomics data

Methodology and tools for genomics and epi-genomics research

Integrative analysis of genomics data

Cancer genomics analysis