2026

1. Lukacsovich D, Young JI, Gomez L, Schmidt MA, Zhang W, Kunkle BW, Chen XS, Martin ER, Wang L*, for the Alzheimer’s Disease Neuroimaging Initiative (2026) From aging to Alzheimer’s disease: concordant brain DNA methylation changes in late life. Genome Medicine https://doi.org/10.1186/s13073-026-01698-8 (code)

2. Lukacsovich D, Young JI, Gomez L, Kunkle BW, Mao Z, Zhang W, Chen X, O’Shea DM, Rundek T, Martin ER, Wang L*, for the Alzheimer’s Disease Neuroimaging Initiative (2026) Blood DNA methylation signature of cognitive reserve moderates the association between CSF tau pathology and memory in prodromal Alzheimer’s disease. Alzheimer’s & Dementia: Translational Research & Clinical Intervention https://doi.org/10.1002/trc2.70257 (code)

3. Zhang W, Lukacsovich D, Young JI, Gomez L, Schmidt MA, Kunkle BW, Chen X, Martin ER, Wang L*, for the Alzheimer’s Disease Neuroimaging Initiative (2026) The Aging Epigenome: Integrative Analyses Reveal Intersection with Alzheimer’s Disease. Geroscience https://doi.org/10.1007/s11357-026-02195-x (code)

4. Zhang W*, Huang H, Wang L, Lehmann BD, Chen XS* (2026) An integrative multiomics random forest framework for robust biomarker discovery, GigaScience, 15:giaf148, https://doi.org/10.1093/gigascience/giaf148 (code

5. Lukacsovich D, Young JI, Gomez L, Zhang W, Kunkle BW, Chen XS, Martin ER, Wang L*, for the Alzheimer’s Disease Neuroimaging Initiative (2026) Longitudinal Blood DNA Methylation Changes During Weight-Loss Intervention and Dementia Progression Risk. Research Square https://doi.org/10.21203/rs.3.rs-10029889/v1  (code)

6. O’Shea D, Wang L, Lukacsovich D, Dhanekula D, Zhang W, Galvin C, Joshi M, Besser L, Rundek T, Galvin JE (2026) Development and external validation of MethylCog: a DNA methylation-based surrogate of general cognitive ability in aging. Alzheimer’s & Dementia 22:e71421. https://doi.org/10.1002/alz.71421

7. Chen L, Ballout F, Chen Z, Thangaretnam K, Que J, Chen XS, McDonald OG, Zaika A, Livingstone A, Giordano S, Shiekhattar R, Lu H, Peng D, El-Rifai W (2026) Acidic bile salts induce APE1-dependent PRDX2 activation to drive oxaliplatin resistance via ferroptosis inhibition, Redox Biology,
95: 104254

8. Lu H, Ballout F, Chen L, Peng D, Chen Z, Soutto M, Cao L, Thangaretnam K, Gokulan RC, Wang TC, Que J, Giordano S, Washington MK, Chen XS, Sun X, Ban Y, McDonald OG, Zaika A, El-Rifai W (2026) Targeting APE1-Redox Function Reverses SOX9-mediated Chemoresistance in Esophageal Adenocarcinoma. Gastroenterology 70(7):1484-1500.