2019

  1. Mallik S, Odom GJ, Gao Z, Gomez L, Chen X*, Wang L*. An evaluation of supervised methods for identifying differentially methylated regions in Illumina methylation arrays. Brief Bioinform. 2019;20(6):2224-35.IF:9.101
  2. Gomez L, Odom GJ, Young JI, Martin ER, Liu L, Chen X, Griswold AJ, Gao Z, Zhang L, Wang L*. coMethDMR: accurate identification of co-methylated and differentially methylated regions in epigenome-wide association studies with continuous phenotypes. Nucleic Acids Research. 2019;47(17):e9 IF:11.147
  3. Gao Y, Li X, Zhi H, Zhang Y, Wang P, Wang Y, Shang S, Fang Y, Shen W, Ning S*, Chen SX*, Li X*. Comprehensive Characterization of Somatic Mutations Impacting lncRNA Expression for Pan-Cancer. Mol Ther Nucleic Acids. 2019;18:66-79. IF:5.919
  4. Wasserman I, Lee LH, Ogino S, Marco MR, Wu C, Chen X, Datta J, Sadot E, Szeglin B, Guillem J, Paty PB, Weiser MR, Nash GM, Saltz L, Barlas A, Manova K, Uppada SB, Elghouayel AE, Nitamoah P, Glickman JN, Hamada T, Kosumi K, Inamura K, Chan AT, Nishihara R, Cercek A, Ganesh K, Kemeny NE, Dhawan P, Yaeger R, Sawyers CL, Carcia-Aguilar J, Glannakis M, Shia J, Smith JJ. SMAD4 loss in colorectal cancer patients correlates with recurrence, loss of immune infiltrate, and chemoresistance. Clinical Cancer Research. 2019; 25(6):1948-1956.IF:10.199
  5. Ganesh K, Wu C, O'Rourke KP, Szeglin BC, Zheng Y, Sauvé CG, Adileh M, Wasserman I, Marco MR, Kim AS, Shady M, Sanchez-Vega F, Karthaus WR, Won HH, Choi SH, Pelossof R, Barlas A, Ntiamoah P, Pappou E, Elghouayel A, Strong JS, Chen CT, Harris JW, Weiser MR, Nash GM, Guillem JG, Wei IH, Kolesnick RN, Veeraraghavan H, Ortiz EJ, Petkovska I, Cercek A, Manova-Todorova KO, Saltz LB, Lavery JA, DeMatteo RP, Massagué J, Paty PB, Yaeger R, Chen X, Patil S, Clevers H, Berger MF, Lowe SW, Shia J, Romesser PB, Dow LE, Garcia-Aguilar J, Sawyers CL, Smith JJ. A rectal cancer organoid platform to study individual responses to chemoradiation. Nature Medicine. 2019;25(10):1607-14. IF:30.641
  6. Mounir M, Lucchetta M, Silva TC, Olsen C, Bontempi G, Chen X, Noushmehr H, Colaprico A, Papaleo E. New functionalities in the TCGAbiolinks package for the study and integration of cancer data from GDC and GTEx. PLoS Computational Biology. 2019;15(3):e1006701. IF:4.428
  7. Toomer KH, Lui JB, Altman NH, Ban Y, Chen X, Malek TR. Essential and non-overlapping IL-2Ra-dependent processes for thymic development and peripheral homeostasis of regulatory T cells. Nature Communications. 2019; 10(1):1037. IF:11.88.
  8. Soutto M, Chen Z, Bhat AA, Wang L, Zhu S, Gomaa A, Bates A, Bhat NS, Pen gD, Belkhiri A, Piazuelo MB, Wanshing MK, Che XS, Peek R, El-Rifai W. Activation of STAT3 signaling is mediated by TFF1 silencing in gastric neoplasia. Nature Communications. 2019; 10:3039 IF:11.88
  9. Camargo JF, Wieder E, Kimble E, Benjamin C, Kolonias DS, Kwon D, Chen XS, Komanduri KV. Deep functional immunophenotyping predicts risk of cytomegalovirus reactivation after hematopoietic cell transplantation. Blood. 2019. 133(8):867-877. IF:16.562
  10. Birnbaum MD, Zhao N, Moorthy BT, Patel DM, Kryvenko ON, Heidman L, Kumar A, Morgan WM, Ban Y, Reis IM, Chen X, Gonzalgo ML, Jorda M, Burnstein KL, Zhang F. Reduced Arginyltransferase 1 is a driver and a potential prognostic indicator of prostate cancer metastasis. Oncogene. 2019;38(6):838-5. IF:6.854
  11. Totiger TM, Srinivasan S, Jala VR, Lamichhane P, Dosch AR, Gaidarski AA, Joshi C, Rangappa S, Castellanos J, Vemula PK, Chen X, Kwon D, Kashikar N, VanSaun M, Merchant NB, Nagathihali NS. Urolithin A, a novel natural compound to target PI3K/AKT/mTOR pathway in pancreatic cancer. Molecular Cancer Therapeutics. 2019. 18(2):301-311.
  12. Caslini C, Hong S, Ban YJ, Chen XS, Ince TA. HDAC7 regulates histone 3 lysine 27 acetylation and transcriptional activity at super-enhancer-associated genes in breast cancer stem cells. Oncogene. 2019;38(39):6599-614. IF:6.854
  13. Chen Z, Li Z, Soutto M, Wang W, Piazuelo MB, Zhu S, Guo Y, Maturana MJ, Corvalan AH, Chen X, Xu Z, El-Rifai WM. Integrated Analysis of Mouse and Human Gastric Neoplasms Identifies Conserved microRNA Networks in Gastric Carcinogenesis. Gastroenterology. 2019;156(4):1127-39 e8.IF:20.877
  14. Chen MS, Lo YH, Chen X, Williams CS, Donnelly JM, Criss ZK, 2nd, Patel S, Butkus JM, Dubrulle J, Finegold MJ, Shroyer NF. Growth Factor-Independent 1 Is a Tumor Suppressor Gene in Colorectal Cancer. Mol Cancer Res. 2019;17(3):697-708. IF:4.484
  15. Patel R, Zhang L, Desai A, Hoenerhoff MJ, Kennedy LH, Radivoyevitch T, Ban Y, Chen XS, Gerson SL, Welford SM. Mlh1 deficiency increases the risk of hematopoietic malignancy after simulated space radiation exposure. Leukemia. 2019;33(5):1135-47.IF:12.104
  16. Rajan SS, Amin AD, Li L, Rolland DC, Li H, Kwon D, Kweh MF, Arumov A, Roberts ER, Yan A, Basrur V, Elenitoba-Johnson KSJ, Chen XS, Puvvada SD, Lussier YA, Bilbao D, Lim MS, Schatz JH. The mechanism of cancer drug addiction in ALK-positive T-Cell lymphoma. Oncogene. 2019.IF:6.854
  17. Short SP, Thompson JJ, Bilotta AJ, Chen X, Revetta FL, Washington MK, Williams CS. Serine Threonine Kinase 17A maintains the epithelial state in colorectal cancer cells. Molecular Cancer Research. 2019; 17(4):882-894. IF:4.484
  18. Toomer KH, Lui JB, Altman NH, Ban Y, Chen X, Malek TR. Essential and non-overlapping IL-2Ralpha-dependent processes for thymic development and peripheral homeostasis of regulatory T cells. Nature Communications. 2019;10(1):1037.IF:11.88
  19. Winterbottom EF, Ban Y, Sun X, Capobianco AJ, Marsit CJ, Chen X, Wang L, Karagas MR, Robbins DJ. Transcriptome-wide analysis of changes in the fetal placenta associated with prenatal arsenic exposure in the New Hampshire Birth Cohort Study. Environ Health. 2019;18(1):100.
  20. Young JI, Sivasankaran SK, Wang L, Ali A, Mehta A, Davis DA, Dykxhoorn DM, Petito CK, Beecham GW, Martin ER, Mash DC, Pericak-Vance M, Scott WK, Montine ST, Vance JM. (2019) Genome-wide brain DNA methylation analysis suggests epigenetic reprogramming in Parkinson disease. Neurol Genet Aug 2019, 5 (4) e342; DOI: 10.1212/NXG.0000000000000342
  21. Gardner OK, Wang L, Booven DV, Whitehead PL, Hamilton-Nelson KL, Adams LD, Starks TD, Hofmann NK, Vance JM, Cuccaro ML, Martin ER, Byrd GS, Haines JL, Bush WS, Beecham GW, Pericak-Vance MA, Griswold AJ (2019) RNA editing alterations in a multi-ethnic Alzheimer disease cohort converge on immune and endocytic molecular pathways. Human Molecular Genetics, 28(18) 3053-3061